Shady should be the focal point in this offense until he's hurt or falls asleep on the field. The Jets gave up Sheldon Richardson, which will hurt their run defense, and they will have trouble scoring, which should give the Bills plenty of opportunity to give it to McCoy.
The Saints are a perfect opponent for Cook, as they gave up the second-most rushing touchdowns in the league and the third-most fantasy points to running backs last season. Cook should be set up as the three-down back and could have a field day at home against the Saints.
I think we'll see Derrick Henry start to cut into Murray's workload as the season goes along, but Week 1 should be solidly in Murray's camp, plus he gets a nice matchup against Oakland, which has seen turnover in its interior line this year.
We aren't going to feel good about projecting the Patriots out of the gate, but there is no doubt that Cooks is a top receiver in a top offense. He'll need to be ignored by Brady to have a poor game in this offense, so until we see something like that, I'll be keeping him high in the rankings.
Baldwin should be the main target in this game for Wilson, and with Tyler Lockett not 100 percent, I expect that is carved in stone.
40. Larry Fitzgerald, Wide Receiver(WR No. 7)WR, Cardinals. Bye: 9.
Fitzgerald always seems to start hot, and this is a good spot for him to do so once again. Add in the fact that John Brown might not be 100 percent, and Fitzgerald should see double-digit targets.
41. Jordan Howard, Running Back(RB No. 8)RB, Bears. Bye: 9.
It will be interesting to see how much work Tarik Cohen gets if the Bears have to go into pass mode to try to keep up with Atlanta, but Howard will be used in the passing game as well and should be the focal point of this offense, especially when it's reasonably close.